The relationship between serum vitamin D and atrial fibrillation (AF) or postoperative atrial fibrillation (POAF) in patients undergoing coronary artery bypass graft (CABG) is still debated. Katritsis DG. The mean age ranged from 57 to 77 years. Finally, 13 studies (14 reports) were included in this meta-analysis (Fig. In contrast, a meta-analysis concluded a weak but positive association between vitamin D deficiency and AF [15]. Among the 13 articles, six were cohort studies [7, 12,13,14, 16], four were nest-case-control (prospective case-control) studies [17,18,19, 29], four [8,9,10,11] were case-control studies. When we excluded the case-control studies, both the older (RR: 0.96, 95%CI: 0.93–1.00) and young people (RR:0.94, 95%CI: 0.89–1.00) showed a weak association between vitamin D deficiency and risk of AF. 2009;169:626–32. Formerly, the role of circulating vitamin D in AF remains unclear. New research presented today at the American Heart Association Scientific Sessions suggests neither vitamin D nor the omega-3 fatty acids found … Cardiovascular Department, the Second Affiliated Hospital of Nanchang University, Nanchang, 330006, Jiangxi, China, Xiao Liu, Wei Wang, Zhaochong Tan, Xin Zhu, Menglu Liu, Rong Wan & Kui Hong, Jiangxi Key Laboratory of Molecular Medicine, Nanchang, Jiangxi, China, You can also search for this author in 2017;69:16–23. We used the robust error meta-regression method (REMR) for the dose-response analysis of the vitamin D level and AF [22, 23]. Both randomized controlled trials and observational studies, reporting data about serum vitamin D level and AF were considered eligible for this meta-analysis. Therefore, we performed a comprehensive meta-analysis to evaluate the shape of the dose-response relation between circulating 25(OH) D concentration and the risk of AF and post-operation AF (POAF) after CABG. Fish oil and vitamin D supplements not effective for preventing atrial fibrillation by American Heart Association A 12 lead ECG showing atrial fibrillation … But not always. To date, results from several observational studies have suggested that patients with vitamin D deficiency were approximately twice as likely to have AF than patients with normal levels (> 30 ng/ml) [8,9,10,11].  @IntermtnMedCtr, Copyright © 2021 by the American Association for the Advancement of Science (AAAS), Harvard-Smithsonian Center for Astrophysics, University of Pennsylvania School of Medicine. Below is a list of common natural remedies used to treat or reduce the symptoms of Atrial+Fibrillation. Introduction. Hour One – September 28, 2020 Hour Two – September 28, 2020. The focus in recent decades has been on the risks of vitamin D and non-skeletal dis-eases, such as cardiovascular disease or atrial fibrillation (AF) [4]. Vitamin D deficiency and risk of cardiovascular disease. J Clin Endocrinol Metab. Atrial fibrillation (AF) is the most common chronic arrhythmia and it increases the risk of cardiovascular morbidity and mortality. Atrial Fibrillation May Not Have Been Caused By Vitamin D It is interesting to note that in patients with excess amounts (greater than 100 ng/mL) of 25-hydroxyvitamin D, a significant increase in hypothyroidism (sluggish thyroid function) was noted by the researchers who presented at the American Heart Association conference. 2014;20:98–103. Plasma 25-hydroxyvitamin D2 and D3 levels and incidence of postoperative atrial fibrillation. For vitamin D, similarly, this is the placebo arm, and you can see again about a 3% incidence of atrial fibrillation. Interestingly, the present dose-response analysis first showed vitamin D deficiency is also a moderate predictor for POAF, and novelty showed a 12% (AF) or 56% (AF post-CABG) increase in the RR per 10-unit increase in vitamin D with evidence of linear association. 2015;100:72–80. Management of atrial fibrillation. Vitamin D, which is synthesized by the body with exposure to sun, is used to regulate calcium and phosphate concentrations in the blood and is essential for growth and development, cellular health, and bone remodeling, a process where mature bone tissue is removed from the skeleton and new bone tissue is formed. Having a vitamin D deficiency is deadly for many diseases and now there may be a correlation between vitamin D and atrial fibrillation. Historically, vitamin D is known for its important role in skeletal disease, [1,2,3]. Bunch and his colleagues examined blood tests from 132,000 patients in the Intermountain Healthcare database at Intermountain Medical Center. Patients did not have any known history of atrial fibrillation, and all had previously received a vitamin D assessment as part of their routine care. Besides the recall bias, the heterogeneity in the study population appeared to be one of the potential reasons. Relation of low vitamin D to nonvalvular persistent atrial fibrillation in Chinese patients. The methodological quality of dose-response meta-analyses needed substantial improvement: a cross-sectional survey and proposed recommendations. I certainly recommend it for patients who want to know more about atrial fibrillation than what they will learn from doctors...." Pierre Jaïs, M.D. Turin A, Bax JJ, Doukas D, Joyce C, Lopez JJ, Mathew V, Pontone G, Shah F, Singh S, Wilber DJ, Rabbat MG. Interactions among Vitamin D, atrial fibrillation, and the renin-Angiotensin-aldosterone system. However, another study which only pooled cohort studies did not support this association [7]. Nine studies (10 reports) [7,8,9,10,11,12,13,14, 16] with 6364 cases/42,776 participants were included in the dose-response analysis of vitamin D and AF. Pak J Med Sci. Belen E, Aykan A, Kalay E, Sungur M, Sungur A, Cetin M. Low-level Vitamin D is associated with atrial fibrillation in patients with chronic heart failure. Further prospective cohort studies are needed to clarify the age difference. vitamin D is an emerging risk factor of AF, and is implicated in the pathophysiology of atrial fibrillation. volume 18, Article number: 73 (2019) Then she insisted that I wear a halter monitor for a week. Adults with higher parathyroid hormone and lower vitamin D levels are more likely to experience an episode of atrial fibrillation compared with those with normal measures, according to … Armin Z, Joachim K, Ernst JB, Tobias B, Jens D, Cornelius K, Gummert JF, Jochen BR. Six studies with 5503 cases/66,139 participants were included [7, 9, 12, 13, 16, 18]. Europace. by contributing institutions or for the use of any information through the EurekAlert system. is a service of the American Association for the Advancement of Science. Patients with atrial fibrillation (AF) have a high risk of stroke. 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